Webb27 dec. 2013 · Pancreatic ductal adenocarcinoma (PDAC) is the fourth most common cause of cancer death in North America. Activating KRAS mutations and Smad4 loss occur in approximately 90% and 55% of PDAC, respectively. While their roles in the early stages of PDAC development have been confirmed in genetically modified mouse models, their … WebbMoreover, INTS8 knockdown also increased the expression of epithelial markers (E-cadherin) and decreased the expression of mesenchymal markers (N-cadherin and vimentin) following the downregulation of SMAD4. In addition, pretreatment with TGF-β1 could partly prevent the decrease in the expression of SMAD4 and EMT markers induced …
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Webb19 feb. 2024 · Proteintech Group. product type : antibody. product name : SMAD4. catalog : 10231-1-AP. quantity : 150UL. price : 299 USD. clonality ... Guo J. KDM6A suppresses … WebbProteintech: SMAD4 Monoclonal antibody: Catalog Number: 60182-1-Ig Citations-Dilutions: Applications: ELISA: Reactivity: human, mouse, rat Product Guarantee: Covers any … gree baltic
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WebbThe membranes were incubated with anti-Mstn GDF8/myostatin polyclonal antibody (dilution 1:1000) or anti-PCSK9 antibody (dilution 1:500), both from Proteintech (Manchester, UK) for 16 h at 4 °C. The membranes were then incubated with an anti-rabbit IgG, HRP-linked antibody for 1 h at room temperature (Cell Signaling Technology, … WebbThe Western blot of S100A4, MYH9, Vimentin, E-Cadherin, p44/42, MAPK, p-AKT473, AKT, Smad2, p-Smad2 in the indicated cells that were coinfected with 10ng/mL TGF- β and … Webb23 nov. 2024 · Background: Circular RNAs (circRNAs), as a class of endogenous RNAs, are implicated in osteosarcoma (OS) progression. However, the functional properties of circDOCK1 in OS have been largely unexplored. The present study demonstrated the regulatory mechanism of circDOCK1 in OS. Methods: QRT-PCR and Western blots were … florists in carlinville illinois