WebAug 5, 2015 · The cellular glycolytic activity was evaluated by measuring the glycolytic index as calculated using the following formula: glycolytic index = (L × G) / O, where L is the cellular lactate generation rate, G is the glucose uptake rate, and O is the oxygen consumption rate . To determine the cellular lactate production rate, cells in the ... WebJan 30, 2013 · When considering the lactate production/glucose consumption ratio (glycolytic index), both harvesting methods led to an increased glycolytic index (Figure 7C for trypsin experiments, glycolytic index = 1.73±0.14 for adherent cells, 2.98±0.26 for trypsinized cells; Figure 8C for collagenase experiment, glycolytic index = 0.89±0.39 for ...
Glycemic Index vs. Load: Tools for Blood Sugar Control - Verywell …
WebAug 29, 2024 · At this maximum point, the glycolytic index (GImax capacity) would be 62.5/109 = 57.3%, making C2C12 myoblasts primarily glycolytic when running at their maximum ATP production rate. Compared with the actual value of JATP production in the presence of glucose (55.2), the bioenergetic capacity was 109/55.2 = 197% of the rate … WebThe high glycolytic rate of tumor cells has often been ascribed to the need for carbons for the synthesis of biomass (Vander Heiden et al, 2009; Hay, 2016). Another increasingly appreciated source of ... Glycolytic index is defined as lactate production/glucose consumption. Glutamine index is defined as glutamate production/glutamine ... fall river elementary schools
Inhibition of Glycolysis in Cancer Cells: A Novel Strategy to …
WebJan 7, 2014 · A prior report discusses the regional dependence of these parameters as well as AG calculated via the glycolytic index—a measure of glucose consumption in excess of that expected on the basis of CMRO 2. AG and the OGI are nearly perfectly inversely correlated (r = −0.98) (Vaishnavi et al., 2010). The regional PET data for each metabolic ... WebIn this study, we constructed a model called aerobic glycolysis index (AGI) as a marker of aerobic glycolysis using genomic data of hepatocellular carcinoma from The Cancer Genome Atlas (TCGA) project. Our results … WebFeb 20, 2024 · Recent studies have highlighted the importance of quantifying glycolytic and oxidative ATP production to obtain a more useful “glycolytic index” that cannot be obtained from measures of extracellular acidification or lactate efflux rates alone [6, 9,10,11]. For this, it is necessary to supplement measurements of nutrient uptake, waste ... convert gpm to lb hr