WebDec 8, 2024 · Gene ID: 320808, updated on 8-Dec-2024 Summary Located in mitochondrion. Orthologous to human DCAF5 (DDB1 and CUL4 associated factor 5). [provided by Alliance of Genome Resources, Apr 2024] Other designations DDB1- and CUL4-associated factor 5, WD repeat domain 22, WD repeat-containing protein 22 WebSep 30, 2024 · Out of the ˜29 CRL4 substrate receptors reported, the DDB1- and CUL4-associated factor 1 (DCAF1) is essential for cellular survival and growth, and its deregulation has been implicated in tumorigenesis. We carried out biochemical and structural studies to examine the structure and mechanism of the CRL4 DCAF1 ligase.
DCAF8 DDB1 and CUL4 associated factor 8 [ (human)]
WebSep 22, 2024 · DCAF8L2 DDB1 and CUL4 associated factor 8 like 2 [ (human)] Gene ID: 347442, updated on 22-Sep-2024 Summary Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2024] Other designations WebThe gene, DGKH, encodes a member of the diacylglycerol kinase enzyme family , while DCAF5 encodes DDB1 and CUL4-associated factor 5 , and LINC02261 is a non-protein-coding lncRNA. None of the genes are known susceptibility loci … new holland hay fork
Entry - *615820 - DDB1- AND CUL4-ASSOCIATED FACTOR 8; DCAF8 …
WebApr 23, 2024 · DDB1- and CUL4-associated factor 8 (DCAF8) is a WD40 repeat-containing protein, which serves as asubstrate receptor for CRL4. The physiological role of DCAF8 is unknown. In this study, we ... WebDec 4, 2024 · DCAF8 DDB1 and CUL4 associated factor 8 [ (human)] Gene ID: 50717, updated on 4-Dec-2024 Summary This gene encodes a WD repeat-containing protein … WebNov 2, 2024 · Furthermore, we revealed that DDB1- and CUL4-associated factor 1 (DCAF1) was downregulated in aged Tregs and was critical to restrain Treg aging via reactive oxygen species (ROS) regulated by glutathione-S-transferase P (GSTP1). Importantly, interfering with GSTP1 and ROS pathways reinvigorated the proliferation … new holland hayliner 268